Now That's What I Call Music! 46 was released on May 7, 2013. The album is the forty-sixth edition of the (U.S.) Now series. It peaked at number 1 and 7 on the Billboard 200 and has been certified 2x Platinum by the RIAA. The compilation includes two songs which reached the Billboard Hot 100: "Locked Out of Heaven" & "Just Give Me a Reason".
The cover is inspired by the NOW 85 UK cover released in the same year.